AB99. Association of mitochondrial DNA copy number in peripheral blood leukocytes with risk and prognosis of prostate
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چکیده
Transl Androl Urol, Vol 3, Suppl 1 September 2014 www.amepc.org/tau © Translational Andrology and Urology. All rights reserved. PI3K/mTOR inhibitor NVP-BEZ235 can significantly inhibit renal cell 786-0 cell proliferation and promote the occurrence of apoptosis; Autophagy inhibitor can significantly improve the NVP-BEZ235 cause 786-0 proliferation inhibition and apoptosis.
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Assessment of mitochondrial DNA copy number in peripheral blood leukocyte of opiate abusers and healthy individuals
Background: Based on the studies, variation in the mitochondrial DNA (mtDNA) copy number in peripheral blood leukocytes is associated with increased susceptibility to diseases including cancer. Opiate abusers are at high risk for diseases. In this study, we measured the mtDNA copy number in peripheral blood leukocytes in a group of opiate abusers compared with those in healthy individuals. Met...
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We investigated whether low mitochondrial DNA copy number (mtDNAcn) in peripheral blood leukocytes at diagnosis was associated with an increased risk of the aggressive form of the tumor and disease progression among localized prostate cancer (PCa) patients. We recruited 1,751 non-Hispanic white men with previously untreated PCa from The University of Texas MD Anderson Cancer Center. mtDNAcn was...
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